Sprouty 4: a possible repressor of Id protein function in breast cancer
This study looks specifically at the Sprouty (Spry) family of four proteins, Spry1, Spry2, Spry3, Spry4. These proteins are reported to be involved in the suppression of tumor growth, and affect the growth of tumors in various ways. The first three proteins of this family, Spry1, Spry2, and Spry3 are well studied in their affects on the suppression of tumor growth in the body. However, the effect that Spry4 has on tumor suppression is less studied, and this paper is interested in looking at how this protein specifically affects another protein, Id Protein. The reason that Id Protein is important is because they are very much present in cancerous tissue, and predicted to be involved in the increase in cell proliferation that occurs in tumorous areas of the body. This study is specifically aimed at entertaining the potential that Spry4 has in regulating Id Protein function, which may have important biological consequences for breast tumor progression and metastasis.