Non-Psychotropic Cannabinoid2 Receptor Agonists Inhibit Breast Cancer Proliferation

Breast cancer is the second leading cause of death in women with nearly 200,000 women diagnosed each year in the U.S. Bone is the most common site for breast cancer metastases, resulting in bone loss, fractures, anemia and pain. Despite marked advances in chemotherapy treatments for early stage breast cancer, once the tumor has metastasized to the bone, few new therapies are effective in slowing disease progression and increasing survival in advanced breast cancer patients. Dr. Vanderah’s team at the University of New England is investigating the use of novel compounds that both inhibit the growth of the breast cancer cells and reduce the cancer induced bone pain and bone loss. Their studies so far suggest that these new medicines may provide breast cancer patients a superior alternative to currently available therapeutics.

Organization: 
University of New England
Researcher: 
Todd Vanderah
Grant Amount Given: 
$105,197
Year Issued: 
2011
Period: 
Annual
Grant Category: 
Research
Types of Cancer: 
Breast
Grant Duration: 
1 Year Pilot Grant

Maine Cancer Foundation Grants to this Organization:

Year Program Amount Category Organization
2017 Methods and Diagnostics for Cancer Detection and Treatment Monitoring $375,000 Screening University of New England
2013 The Role of the Kappa Opioid Receptor in Regulating Cancer Proliferation in Vitro and In Vivo $50,000 Research University of New England
2013 Improving the Treament of Cancer Related Pain $22,540 Education University of New England
2012 Feasibility of Using SEER-Medicare Data to Assess the Influence of ESA Policy Changes on Outcomes $55,936 Research University of New England
2012 The Role of IL-6 Signaling in Cancer-induced Bone Pain $139,633 Research University of New England
2011 Non-Psychotropic Cannabinoid2 Receptor Agonists Inhibit Breast Cancer Proliferation $105,197 Research University of New England
2008 Role of Delta Opioid Receptors in Bone Cancer $81,995 Research University of New England
2002 Occupational Therapy Education $5,000 Education University of New England
2001 The Impact of Chemotherapy on Memory in Women with Breast Cancer $5,074 Research University of New England