Inceptive Role of miR-199b in Acute Myeloid Leukemia
Dr. Sathyanarayana is addressing acute myeloid leukemia (AML), seeking to define the role of certain biomarkers in the disease. One of the major objectives of his work is the development of novel prognostic factors including microRNAs. Dr. Sathyanarayana will seek to understand the potential of microRNAs as a tool to distinguish subgroups of AML patients with differing prognoses. The study will pave the way for direct testing of incoming AML cases for aberrant microRNA expressions and will provide guidelines to increase the sample size for next phase of clinical translational research. The outcome will be very important for laying strong framework and foundation for more in-depth and large scale studies with significant clinical implications for AML.